Charles A. Scanga, Andre Bafica, Carl G. Feng, Allen W. Cheever, Sara Hieny and Alan Sher. MyD88-Deficient Mice Display a Profound Loss in Resistance to Mycobacterium tuberculosis Associated with Partially Impaired Th1 Cytokine and Nitric Oxide Synthase 2 Expression. Infect. Immun. April 2004 vol. 72 no. 4 2400-2404.

           Russell P. Bowler, Mike Nicks, Karen Tran, Grant Tanner, Ling-Yi Chang, Scott K. Young, and G. Scott Worthen. Extracellular Superoxide Dismutase Attenuates Lipopolysaccharide-Induced Neutrophilic Inflammation. American Journal of Respiratory Cell and Molecular Biology, Vol. 31, No. 4 (2004), pp. 432-439.

           Pilar Domenech, Michael B. Reed, Cynthia S. Dowd, Claudia Manca, Gilla Kaplan and Clifton E. Barry III. The Role of MmpL8 in Sulfatide Biogenesis and Virulence of Mycobacterium tuberculosis. The Journal of Biological Chemistry, Vol. 279, No. 20, 2004, pp. 21257–21265.


           Eric R. Secor Jr., William F. Carson IV, Michelle M. Cloutier, Linda A. Guernsey, Craig M. Schramm, Carol A. Wu, Roger S. Thrall. Bromelain exerts anti-inflammatory effects in an ovalbumin-induced murine model of allergic airway disease. Cellular Immunology, Volume 237, Issue 1, September 2005, Pages 68–75.

           Annette Robichaud, Stephanie A. Tuck, Stacia Kargman, John Tam, Elizabeth Wong, Mark Abramovitz, James Mortimer, Helen E. Burston, Paul Masson, Jeremy Hirota, Deborah Slipetz, Brian Kennedy, Gary O'Neill, and Steven Xanthoudakis. Gob-5 Is Not Essential for Mucus Overproduction in Preclinical Murine Models of Allergic Asthma. American Journal of Respiratory Cell and Molecular Biology, Vol. 33, No. 3 (2005), pp. 303-314.


           C.M. Schramm, L. Guernsey, E. Secor, R.S. Thrall. Tolerance induced by chronic inhaled antigen in a murine asthma model is not mediated by endotoxin. Biochimica et Biophysica Acta. (BBA) - Molecular Basis of Disease, Volume 1762, Issue 5, May 2006, Pages 499–501.

           Prakash M. Kabbur, William F. Carson IV, Linda Guernsey, Eric R. Secor Jr., Roger S. Thrall. Craig M. Schramm. Interleukin-10 does not mediate inhalational tolerance in a chronic model of ovalbumin-induced allergic airway disease. Cellular Immunology, Volume 239, Issue 1, January 2006, Pages 67–74.

           Liana Tsenova, Ryhor Harbacheuski, Evette Ellison, Claudia Manca, and Gilla Kaplan. Aerosol Exposure System for Rabbits: Application to M. Tuberculosis Infection. Applied Biosafety, 2006, 11 (1) pp. 7-14.


           Eric R. Secor Jr, William F. Carson IV, Anurag Singh, Mellisa Pensa, Linda A. Guernsey, Craig M. Schramm, and Roger S. Thrall. Oral Bromelain Attenuates Inflammation in an Ovalbumin-Induced Murine Model of Asthma. Evidence-Based Complementary and Alternative Medicine, Volume 5 (2008), Issue 1, Pages 61-69.

           Anurag Singh, Roger S Thrall, Linda A Guernsey, William F Carson IV, Eric R Secor Jr, Robert E Cone, Thiruchandurai V Rajan and Craig M Schramm. Subcutaneous late phase responses are augmented during local inhalational tolerance in a murine asthma model. Immunology and Cell Biology (2008) 86, 535–538, May 2008.

           Carol A. Wu, John J. Peluso, John D. Shanley, Lynn Puddington, Roger S. Thrall. Murine Cytomegalovirus Influences Foxj1 Expression, Ciliogenesis, and Mucus Plugging in Mice with Allergic Airway Disease. The American Journal of Pathology, Volume 172, Issue 3, March 2008, Pages 714–724.

           Carson IV W.F., Guernsey L.A., Singh A., Vella A.T., Schramm C.M., Thrall R.S. Accumulation of Regulatory T Cells in Local Draining Lymph Nodes of the Lung Correlates with Spontaneous Resolution of Chronic Asthma in a Murine Model. Int Arch Allergy Immunol, 2008, Vol. 145, No. 3:231-243.


           Crystal L. Loving, Taruna Khurana, Manuel Osorio, Gloria M. Lee, Vanessa K. Kelly, Scott Stibitz and Tod J. Merkel. Role of Anthrax Toxins in Dissemination, Disease Progression, and Induction of Protective Adaptive Immunity in the Mouse Aerosol Challenge Model. Infect. Immun. January 2009 vol. 77 no. 1 255-265.

           Crystal L. Loving, Manuel Osorio, Yun-Gi Kim, Gabriel Nuñez, Molly A. Hughes and Tod J. Merkel. Nod1/Nod2-Mediated Recognition Plays a Critical Role in Induction of Adaptive Immunity to Anthrax after Aerosol Exposure. Infect. Immun., October 2009, vol. 77, no. 10, 4529-4537.

           D. Saini, R. M. Buller, A. S. Biris and P. Biswas. Characterization of a Nose-Only Inhalation Exposure System for Ectromelia Virus Infection of Mice. Particulate Science and Technology: An International Journal, Volume 27, Issue 2, 2009, p.152-165.

           Shanshan Cai, Rachel L. Zemans, Scott K. Young, G. Scott Worthen, and Samithamby Jeyaseelan. Myeloid Differentiation Protein-2–Dependent and –Independent Neutrophil Accumulation during Escherichia coli Pneumonia. Am J Respir Cell Mol Biol. Jun 2009; 40(6): 701–709.

           Adam P. Matson, Roger S. Thrall, Ektor Rafti, and Lynn Puddington. Breastmilk from Allergic Mothers Can Protect Offspring from Allergic Airway Inflammation. Breastfeeding Medicine. September 2009, 4(3): 167-174.


           Adam P Matson, Roger S Thrall, Ektor Rafti, Elizabeth G Lingenheld and Lynn Puddington. IgG transmitted from allergic mothers decreases allergic sensitization in breastfed offspring. Clinical and Molecular Allergy, 2010, 8:9.

           Carol A. Wu, John J. Peluso, Li Zhu, Elizabeth G. Lingenheld, Sharale T. Walker, Lynn Puddington. Bronchial epithelial cells produce IL-5: Implications for local immune responses in the airways. Cellular Immunology, Volume 264, Issue 1, 2010, Pages 32–41.

           Richard S Tuttle, William A Sosna, Deirdre E Daniels, Sara B Hamilton and John A Lednicky. Design, assembly, and validation of a nose-only inhalation exposure system for studies of aerosolized viable influenza H5N1 virus in ferrets. Virology Journal 2010, 7:135.

           John A Lednicky, Sara B Hamilton, Richard S Tuttle, William A Sosna, Deirdre E Daniels, David E Swayne. Ferrets develop fatal influenza after inhaling small particle aerosols of highly pathogenic avian influenza virus A/Vietnam/1203/2004 (H5N1). Virology Journal 2010, 7:231.

           Jorrit J. Hofstra, Alexander P. Vlaar, Alexander D. Cornet, Barry Dixon, Joris J. Roelofs, Goda Choi, Tom van der Poll, Marcel Levi, and Marcus J. Schultz. Nebulized Anticoagulants Limit Pulmonary Coagulopathy, But Not Inflammation, in a Model of Experimental Lung Injury. Journal of Aerosol Medicine and Pulmonary Drug Delivery, April 2010, 23(2): 105-111.


           Kerstin J. Williams, Helena I. Boshoff, Nitya Krishnan, Jacqueline Gonzales, Dirk Schnappinger, Brian D. Robertson. The Mycobacterium tuberculosis β-oxidation genes echA5 and fadB3 are dispensable for growth in vitro and in vivo. Tuberculosis, Volume 91, Issue 6, November 2011, Pages 549–555.

           Brendan Prideaux, Véronique Dartois, Dieter Staab, Danielle M. Weiner, Anne Goh, Laura E. Via, Clifton E. Barry III, and Markus Stoeckli. High-Sensitivity MALDI-MRM-MS Imaging of Moxifloxacin Distribution in Tuberculosis-Infected Rabbit Lungs and Granulomatous Lesions. Analytical Chemistry, 2011, 83 (6), pp 2112–2118.

           Selvakumar Subbian, Liana Tsenova, Paul O'Brien, Guibin Yang, Mi-Sun Koo, Blas Peixoto, Dorothy Fallows, Jerome B. Zeldis, George Muller, Gilla Kaplan. Phosphodiesterase-4 Inhibition Combined with Isoniazid Treatment of Rabbits with Pulmonary Tuberculosis Reduces Macrophage Activation and Lung Pathology. The American Journal of Pathology, Volume 179, Issue 1, July 2011, Pages 289–301.


           Maria C. Kjellssona, Laura E. Via, Anne Goh, Danielle Weiner, Kang Min Low, Steven Kern, Goonaseelan Pillai, Clifton E. Barry III and Véronique Dartois. Pharmacokinetic Evaluation of the Penetration of Antituberculosis Agents in Rabbit Pulmonary Lesions. Antimicrob. Agents Chemother. January 2012 vol. 56 no. 1 446-45.

           Guoyan Cheng, Xiaomei Yuan, Matthew S. Tsai, Eckhard R. Podack, Aixin Yu and Thomas R. Malek. IL-2 Receptor Signaling Is Essential for the Development of Klrg1+ Terminally Differentiated T Regulatory Cells. The Journal of Immunology August 15, 2012 vol. 189 no. 4 1780-179.

           Chad J. Roy, Satheesh K. Sivasubramani, Noton K. Dutta, Smriti Mehra, Nadia A. Golden, Stephanie Killeen, James D. Talton, Badre E. Hammoud, Peter J. Didier and Deepak Kaushal. Aerosolized Gentamicin Reduces the Burden of Tuberculosis in a Murine Model. Antimicrob. Agents Chemother. February 2012, vol. 56, no. 2:883-886.

           Nicole N. Driessen, Helena I. M. Boshoff, Janneke J. Maaskant, Sebastiaan A. C. Gilissen, Simone Vink, Astrid M. van der Sar, Christina M. J. E. Vandenbroucke-Grauls, Carole A. Bewley, Ben J. Appelmelk and Jeroen Geurtsen. Cyanovirin-N Inhibits Mannose-Dependent Mycobacterium–C-Type Lectin Interactions but Does Not Protect against Murine Tuberculosis. The Journal of Immunology October 1, 2012 vol. 189 no. 7 3585-3592.

           Eric R. Secor Jr., Sonali J. Shah, Linda A. Guernsey, Craig M. Schramm, Roger S. Thrall. Bromelain Limits Airway Inflammation in an Ovalbumin-induced Murine Model of Established Asthma. Alternative Therapies in Health & Medicine. Sep/Oct2012, Vol. 18 Issue 5, p9-17. 9p.

           S. Paveglio, L. Puddington, E. Rafti and A. P. Matson. FcRn-mediated intestinal absorption of IgG anti-IgE/IgE immune complexes in mice. Clinical & Experimental Allergy, Volume 42, Issue 12, pages 1791–1800, December 2012.

           R.S. McDonald, A.R. Sambol, B.K. Heimbuch, T.L. Brown2, S.H. Hinrichs and J.D. Wander. Proportional mouse model for aerosol infection by influenza. Journal of Applied Microbiology, Volume 113, Issue 4, pages 767–778, October 2012.

           Laura E. Via, Dan Schimel, Danielle M. Weiner, Veronique Dartois, Emmanuel Dayao, Ying Cai, Young-Soon Yoon, Matthew R. Dreher, Robin J. Kastenmayer, Charles M. Laymon, J. Eoin Carny, JoAnne L. Flynn, Peter Herscovitch and Clifton E. Barry III. Infection Dynamics and Response to Chemotherapy in a Rabbit Model of Tuberculosis using [18F]2-Fluoro-Deoxy-d-Glucose Positron Emission Tomography and Computed Tomography. Antimicrob. Agents Chemother. August 2012, vol. 56, no. 8:4391-4402.


           Laura E. Via, Danielle M. Weiner, Daniel Schimel, Philana Ling Lin, Emmanuel Dayao, Sarah L. Tankersley, Ying Cai, M. Teresa Coleman, Jaime Tomko, Praveen Paripati, Marlene Orandle, Robin J. Kastenmayer, Michael Tartakovsky, Alexander Rosenthal, Damien Portevin, Seok Yong Eum, Saher Lahouar, Sebastien Gagneuxj, Douglas B. Young, JoAnne L. Flynn and Clifton E. Barry III. Differential Virulence and Disease Progression following Mycobacterium tuberculosis Complex Infection of the Common Marmoset (Callithrix jacchus). Infect. Immun. August 2013, vol. 81, no. 8:2909-2919.


           Amy L. Hartman, Diana S. Powell, Laura M. Bethel, Amy L. Caroline, Richard J. Schmid, Tim Oury and Douglas S. Reed. Aerosolized Rift Valley Fever Virus Causes Fatal Encephalitis in African Green Monkeys and Common Marmosets. J. Virol. February 2014 vol. 88 no. 4 2235-2245.

           Maria C. Kjellsson, Laura E. Via, Anne Goh, Danielle Weiner, Kang Min Low, Steven Kern, Goonaseelan Pillai, Clifton E. Barry III and Véronique Dartois. Penetration of anti-tuberculosis agents in rabbit pulmonary lesions: a pharmacokinetic evaluation. Antimicrobial Agents and Chemotherapy, April 2014, volume 58, issue 4.


           Paul R. Houin, Livia A. Veress, Raymond C. Rancourt, Tara B. Hendry-Hofer, Joan E. Loader, Jacqueline S. Rioux, Rhonda B. Garlick and Carl W. White. Intratracheal heparin improves plastic bronchitis due to sulfur mustard analog. Pediatric Pulmonology, Volume 50, Issue 2, pages 118–126, February 2015.

           Isaac G. Sakala, Lars Kjer-Nielsen, Christopher S. Eickhoff, Xiaoli Wang, Azra Blazevic, Ligong Liu, David P. Fairlie, Jamie Rossjohn, James McCluskey, Daved H. Fremont, Ted H. Hansen, and Daniel F. Hoft. Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites. The Journal of Immunology, June 10, 2015, 1402545.

           Paul M. Beringer, Timothy J. Bensman, Henry Ho, Melissa Agnello, Nicole Denovel, Albert Nguyen, Annie Wong-Beringer, Rosemary She, Dat Q. Tran, Samuel M. Moskowitz, and Michael E. Selsted. Rhesus u-defensin-1 (RTD-1) exhibits in vitro and in vivo activity against cystic fibrosis strains of Pseudomonas aeruginosa. Journal of Antimicrobial Chemotherapy, October 3, 2015. DOI:10.1093/jac/dkv301.


            Rasha Hammamieh, Seid Muhie, Richard Borschel, Aarti Gautam, Stacy-Ann Miller, Nabarun Chakraborty, Marti Jett. Temporal Progression of Pneumonic Plague in Blood of Nonhuman Primate: A Transcriptomic Analysis. March 22, 2016 DOI: 10.1371/journal.pone.0151788.

            John Lednicky, Maohua Pan, Julia Loeb, Hsin Hsieh, Arantzazu Eiguren-Fernandez, Susanne Hering, Z. Hugh Fan & Chang-Yu Wu. Highly efficient collection of infectious pandemic Influenza H1N1 virus (2009) through laminar-flow water based condensation. Aerosol Science and Technology, April 1, 2016 DOI:10.1080/02786826.2016.1179254.

           Rasha Hammamieh, Seid Muhie, Richard Borschel, Aarti Gautam, Stacy-Ann Miller, Nabarun Chakraborty, Marti Jett. Temporal Progression of Pneumonic Plague in Blood of Nonhuman Primate: A Transcriptomic Analysis. PLoS ONE, March 2016 DOI:10.1371/journal.pone.0151788.


            C B Mathias, C M Schramm, L A Guernsey, C A Wu, S H Polukort, J Rovatti, J Ser-Dolansky, E Secor, S S Schneider, R S Thrall, H L Aguila. IL-15-deficient mice develop enhanced allergic responses to airway allergen exposure. Clin Exp Allergy, February 2017 DOI: 10.1111/cea.12886.

            Laila Ladhani, Gaspard Pardon, Hanne Meeuws, Liesbeth van Wesenbeeck, Kristiane Schmidt, Lieven Stuyver, and Wouter van der Wijngaart. Sampling and detection of airborne influenza virus towards point-of-care applications. PLoS ONE, March 2017 DOI: 10.1371.

            Ashutosh Kumar, Mathilde Triquigneaux, Jennifer Madenspacher, Kalina Ranguelova, John J. Bang, Michael B. Fessler, and Ronald P. Masona. Sulfite-induced protein radical formation in LPS aerosol-challenged mice: Implications for sulfite sensitivity in human lung disease. Redox Biology, December 2017. DOI: 10.1016/j.redox.2017.12.014.


           Lawrence S. Zisman. . (2019) US Patent Application No. US20180193336A1.

           Eckhard R. Podack, Taylor H. Schreiber, and Dietlinde-Maria Wolf. (2019) US Patent Application No. US20180230226A1

           Beites, T., O’Brien, K., Tiwari, D. et al. Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development. Nat Commun 10, 4970 (2019) doi:10.1038/s41467-019-12956-2

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