Bio-Aerosol Nebulizing Generator

The Bio-Aerosol Nebulizing Generator (BANG) is a unique nebulizer for the generation of aqueous aerosols at a low air flow rate. While the BANG is based on the aerosolization principle of the Collison nebulizer, the design has been modified to minimize foaming of protein solutions and, thus, increase viability of microorganisms in bio-aerosols while maximizing aerosol output.

The key feature of the BANG is its ability to be operated in a one-pass mode with the liquid feed being controlled externally by a metering pump. This avoids the recirculation of bio-aerosol solutions that can produce low viability due to the physical damage sustained by the cells when subjected to repeated sheer and impact forces. The standard BANG models operate between 2 and 16 liters per minute depending upon the number of jets and input air pressure.

Functionality of the BANG is based on aerosol production caused when incoming air forced through a small orifice meets a flow of incoming solution. The solution may be self-aspirated from the BANG jar (in recirculation mode) or externally pumped (in one-pass mode). The solution is turned into a fine mist that disperses into an even finer mist when the initial droplets impact the walls of the aerosolization chamber. These smaller droplets are released from the outlet and directed into a desired inhalation exposure unit such as the CH Technologies nose-only exposure unit. Baffles on the outlet (for models with vertical discharge) or a curved outlet tube (for models with horizontal discharge) scrub the larger droplets from the outgoing aerosol and recycle them into the fluid reservoir for reuse or disposal.

With the new CHεST Controller, the BANG can simulate conditions and particles produced during respiratory exhalation. The user inputs the length of the aerosol generation period and the interval in between generation. The syringe pump works with the system to deliver test article solution at programable feed rate.

  • Increased viability for vegetative bacteria aerosols
  • Minimization of foaming when used with proteinic solutions
  • Can be operated in both recirculation and one-pass mode
  • Accurate control of liquid feed rate in one-pass mode
  • Resistant to frequent decontamination procedures with chemicals or autoclaving
  • Wide range of output
  • High aerosolization efficiency
  • Aerobiology
  • Biodefense Research
  • Drug Discovery
  • Aerosol Exposure Challenges
  • Ideal for Aerosolization of Proteinic and Bacterial Solutions


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