E-Cigarette Aerosol Generator

The patent pending system designed and manufactured by e~Aerosols allows users to select operating temperature of the coil using a novel, positive pressure approach that utilizes conditioned and scrubbed, particle-free air for aerosol generation. All exposure puffing parameters are customizable and can be easily preprogrammed or set by the user. The Electronic Cigarette Aerosol Generator (ECAG) platforms are designed specifically for electronic cigarettes and all vape products from the ground up.

User Customizable Parameters Include: Exposure Duration Start/Stop Time, Puff Duration, Puff Volume, Inter-Puff Duration or Break between Puff Cluster, and Operating Voltage/Wattage or Coil Temperature. Puff regimes are preprogrammed at the factory or can be set by the user, allowing a fast start up at the push of a button. Multi-Port models allow users to achieve high mass concentrations with up to 24-hrs* of automated continuous aerosol generation with no operator required.

This novel positive pressure system allows for a more accurate physicochemical characterization and delivery at the ENDS’ exhaust port, reducing aerosol aging, tube deposition, and eliminating artifacts that could be introduced from background air. Alternative devices that use negative pressure vacuum systems require aerosols to travel through pumps and additional hosing, ultimately affecting physicochemical characteristics. Users can choose to study any particular puff desired, such as the first 10 puffs, middle, or last 10 puffs of an e-cigarette.

An ohmmeter built into the unit allows the electrical resistance associated with each cartridge to be determined. The Ohmmeter also provides users a quick way to determine faulty e-cigarettes or degraded coils after use. The ECAG is able to simulate all standard e-cigarette batteries and voltages, thus allowing the study of voltage effects on aerosol production and composition and eliminating the need to use or recharge batteries during generation. The ECAG was designed to accommodate one piece disposable electronic cigarettes (i.e., cig-alikes), in addition to the refillable tank/clearomizer 2nd thru 4th generation devices. An optional sub-ohm high-volume upgrade is also available. Additional upgrades include positive pressure aerosolization of heat-not-burn devices or JUUL pods.

(*Puff Regime dependent)
  • Easier and more accurate aerosol characterization at the exhaust
  • Mimic battery types at various voltages
  • Clean, dry, particle free carrier gas
  • Adjustable Voltage of 2nd and 3rd/4th gGenerations Tanks/E-cigarettes
  • Precise Positive Pressure Delivery at E-cigarette Exhaust
  • Reduces Aerosol Resonance Time and Tube Deposition
  • Undiluted or Immediate Dilution Aerosol Generation With Specific Configurations
  • Eliminate Artifacts Due to Aerosol Flow Through Vacuum Pump
  • Eliminate Battery Drain Affecting Voltage and Aerosol Production
  • Eliminate the Need to Recharge Batteries
  • Multi-Port Models allow for Continuous or High Mass Concentrations
  • Generate up to 24 Hours* of Continuous Aerosol With No Operator Required
  • Data Acquisition Capability, Puff Count, Power/Voltage, Coil Resistance
  • Various protocols, regimens, cigarette sizes, & tests are supported
  • Sub-Ohm 400 Watt Capability, Juul Port, and Heat Not Burn Port (Optional)
  • In Vivo and In Vitro Exposure Research
  • Electronic cigarette test aerosol generation
  • Aerosol physicochemical analysis
  • Drug Discovery

           Jiayuan Zhao, Jordan Nelson, Oluwabunmi Dada, Georgios Pyrgiotakis, Ilias G. Kavouras & Philip Demokritou. (Harvard School of Public Health, University of Alabama) Assessing electronic cigarette emissions: linking physico-chemical properties to product brand, e-liquid flavoring additives, operational voltage and user puffing patterns. Inhalation Toxicology, March 2018.

           Jiayuan Zhao, Yipei Zhang, Jennifer D. Sisler, Justine Shaffer, Stephen S. Leonard, Anna M. Morris, Yong Qian, Dhimiter Bello, Philip Demokritou. (Harvard School of Public Health, University of Massachusetts Lowell, NIOSH) Assessment of reactive oxygen species generated by electronic cigarettes using acellular and cellular approaches. Journal of Hazardous Materials, Feb. 2018.

           Hyun-Wook Lee, Sung-Hyun Park, Mao-wen Weng, Hsiang-Tsui Wang, William C. Huang, Herbert Lepor, Xue-Ru Wu, Lung-Chi Chen and Moon-shong Tang. (NYU School of Medicine) E-cigarette smoke damages DNA and reduces repair activity in mouse lung, heart, and bladder as well as in human lung and bladder cells. Proceedings of the National Academy of Sciences (PNAS), Jan. 2018.

  For more references, please visit the Publications Section.


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